A Hypomethylating Variant of MTHFR, 677C>T, Blunts the Neural Response to Errors in Patients with Schizophrenia and Healthy Individuals

BACKGROUND: Responding to errors is a critical first step in learning from mistakes, a process that is abnormal in schizophrenia. To gain insight into the neural and molecular mechanisms of error processing, we used functional MRI to examine effects of a genetic variant in methylenetetrahydrofolate...

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Détails bibliographiques
Auteurs principaux: Roffman, Joshua L., Nitenson, Adam Z., Agam, Yigal, Isom, Marlisa, Friedman, Jesse S., Dyckman, Kara A., Brohawn, David G., Smoller, Jordan W., Goff, Donald C., Manoach, Dara S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182200/
https://ncbi.nlm.nih.gov/pubmed/21980405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025253
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