Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α

The generation of functional arterial endothelial cells (aECs) from embryonic stem cells (ESCs) holds great promise for vascular tissue engineering. However, the mechanisms underlying their generation and the potential of aECs in revascularizing ischemic tissue are not fully understood. Here, we obs...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Tsang, Kit Man, Hyun, James S., Cheng, Kwong Tai, Vargas, Micaela, Mehta, Dolly, Ushio-Fukai, Masuko, Zou, Li, Pajcini, Kostandin V., Rehman, Jalees, Malik, Asrar B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599266/
https://ncbi.nlm.nih.gov/pubmed/28781077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.07.001
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