Cytoplasmic and Nuclear TAZ Exert Distinct Functions in Regulating Primed Pluripotency

Mouse epiblast stem cells (mEpiSCs) and human embryonic stem cells (hESCs) are primed pluripotent stem cells whose self-renewal can be maintained through cytoplasmic stabilization and retention of β-catenin. The underlying mechanism, however, remains largely unknown. Here, we show that cytoplasmic β...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Zhou, Xingliang, Chadarevian, Jean Paul, Ruiz, Bryan, Ying, Qi-Long
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599246/
https://ncbi.nlm.nih.gov/pubmed/28844657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.07.019
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