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Cytoplasmic and Nuclear TAZ Exert Distinct Functions in Regulating Primed Pluripotency
Mouse epiblast stem cells (mEpiSCs) and human embryonic stem cells (hESCs) are primed pluripotent stem cells whose self-renewal can be maintained through cytoplasmic stabilization and retention of β-catenin. The underlying mechanism, however, remains largely unknown. Here, we show that cytoplasmic β...
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Publicado no: | Stem Cell Reports |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599246/ https://ncbi.nlm.nih.gov/pubmed/28844657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.07.019 |
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