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NK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCs

HLA haplotype-homozygous (HLA-homo) induced pluripotent stem cells (iPSCs) are being prepared to be used for allogeneic transplantation of regenerated tissue into recipients carrying an identical haplotype in one of the alleles (HLA-hetero). However, it remains unaddressed whether natural killer (NK...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Ichise, Hiroshi, Nagano, Seiji, Maeda, Takuya, Miyazaki, Masaki, Miyazaki, Yuki, Kojima, Hiroto, Yawata, Nobuyo, Yawata, Makoto, Tanaka, Hidenori, Saji, Hiroh, Masuda, Kyoko, Kawamoto, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599245/
https://ncbi.nlm.nih.gov/pubmed/28867344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.07.020
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