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Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function

Interactions between killer cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) class I ligands regulate the development and response of human natural killer (NK) cells. Natural selection drove an allele-level group A KIR haplotype and the HLA-C1 ligand to unusually high freq...

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Detalhes bibliográficos
Main Authors: Yawata, Makoto, Yawata, Nobuyo, Draghi, Monia, Little, Ann-Margaret, Partheniou, Fotini, Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118260/
https://ncbi.nlm.nih.gov/pubmed/16533882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051884
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