MHC class I–specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

Variegated expression of 6 inhibitory HLA class I–specific receptors on primary NK cells was studied using high-dimension flow cytometry in 58 humans to understand the structure and function of NK-cell repertoires. Sixty-four subsets expressing all possible receptor com-binations were present in eac...

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Detalhes bibliográficos
Main Authors: Yawata, Makoto, Yawata, Nobuyo, Draghi, Monia, Partheniou, Fotini, Little, Ann-Margaret, Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532809/
https://ncbi.nlm.nih.gov/pubmed/18583565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-143727
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