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How did variable NK-cell receptors and MHC class I ligands influence immunity, reproduction and human evolution?

Natural killer (NK) cells have roles in immunity and reproduction that are controlled by variable receptors that recognize MHC class I molecules. The variable NK cell receptors found in humans are specific to simian primates, where they have progressively co-evolved with MHC class I molecules. The e...

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Detalhes bibliográficos
Main Authors: Parham, Peter, Moffett, Ashley
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956658/
https://ncbi.nlm.nih.gov/pubmed/23334245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3370
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