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Skin cancer risk is modified by KIR/HLA interactions that influence the activation of natural killer immune cells
Natural killer (NK) cell phenotype is partially mediated through binding of killer immunoglobulin-like receptors (KIR) with HLA class I ligands. The KIR gene family is highly polymorphic and not well captured by standard GWAS approaches. Here we tested the hypothesis that variations in KIR gene cont...
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| Veröffentlicht in: | Cancer Res |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715977/ https://ncbi.nlm.nih.gov/pubmed/26744525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0547 |
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