Skin cancer risk is modified by KIR/HLA interactions that influence the activation of natural killer immune cells

Natural killer (NK) cell phenotype is partially mediated through binding of killer immunoglobulin-like receptors (KIR) with HLA class I ligands. The KIR gene family is highly polymorphic and not well captured by standard GWAS approaches. Here we tested the hypothesis that variations in KIR gene cont...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Vineretsky, Karin A., Karagas, Margaret R., Christensen, Brock C., Kuriger-Laber, Jacquelyn K., Perry, Ann E., Storm, Craig A., Nelson, Heather H.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715977/
https://ncbi.nlm.nih.gov/pubmed/26744525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0547
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