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Control of AMPA receptor activity by the extracellular loops of auxiliary proteins

At synapses throughout the mammalian brain, AMPA receptors form complexes with auxiliary proteins, including TARPs. However, how TARPs modulate AMPA receptor gating remains poorly understood. We built structural models of TARP-AMPA receptor complexes for TARPs γ2 and γ8, combining recent structural...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Riva, Irene, Eibl, Clarissa, Volkmer, Rudolf, Carbone, Anna L, Plested, Andrew JR
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599240/
https://ncbi.nlm.nih.gov/pubmed/28871958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28680
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