Control of AMPA receptor activity by the extracellular loops of auxiliary proteins

At synapses throughout the mammalian brain, AMPA receptors form complexes with auxiliary proteins, including TARPs. However, how TARPs modulate AMPA receptor gating remains poorly understood. We built structural models of TARP-AMPA receptor complexes for TARPs γ2 and γ8, combining recent structural...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Riva, Irene, Eibl, Clarissa, Volkmer, Rudolf, Carbone, Anna L, Plested, Andrew JR
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Structural Biology and Molecular Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599240/
https://ncbi.nlm.nih.gov/pubmed/28871958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28680
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