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Control of AMPA receptor activity by the extracellular loops of auxiliary proteins

At synapses throughout the mammalian brain, AMPA receptors form complexes with auxiliary proteins, including TARPs. However, how TARPs modulate AMPA receptor gating remains poorly understood. We built structural models of TARP-AMPA receptor complexes for TARPs γ2 and γ8, combining recent structural...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Riva, Irene, Eibl, Clarissa, Volkmer, Rudolf, Carbone, Anna L, Plested, Andrew JR
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599240/
https://ncbi.nlm.nih.gov/pubmed/28871958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28680
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