Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis

Hematopoietic stem cells arise from mesoderm-derived hemogenic endothelium (HE) during embryogenesis in a process termed endothelial-hematopoietic transition (EHT). To better understand the gene networks that control this process, we investigated the role of the transcription factor HEB (TCF12) by d...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Stem Cell Reports
Hlavní autoři: Li, Yang, Brauer, Patrick M., Singh, Jastaranpreet, Xhiku, Sintia, Yoganathan, Kogulan, Zúñiga-Pflücker, Juan Carlos, Anderson, Michele K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599183/
https://ncbi.nlm.nih.gov/pubmed/28803914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.07.011
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky