טוען...
Notch and the pre-TCR coordinate thymocyte proliferation by induction of the SCF subunits Fbxl1 and Fbxl12
Proliferation is tightly regulated during T cell development and is limited to immature CD4(−)CD8(−) thymocytes. The major proliferative event is initiated at the ‘β-selection’ stage following successful rearrangement of Tcrβ and is triggered by and dependent on concurrent signaling by Notch and the...
שמור ב:
| הוצא לאור ב: | Nat Immunol |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6754294/ https://ncbi.nlm.nih.gov/pubmed/31451788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0469-z |
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