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Molecular dynamics of conformation-specific dopamine transporter-inhibitor complexes

The recreational psychostimulant cocaine inhibits dopamine reuptake from the synapse, resulting in excessive stimulation of postsynaptic dopamine receptors in brain areas associated with reward and addiction. Cocaine binds to and stabilizes the outward- (extracellular-) facing conformation of the do...

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Bibliografski detalji
Izdano u:J Mol Graph Model
Glavni autori: Jean, Bernandie, Surratt, Christopher K., Madura, Jeffry D.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599167/
https://ncbi.nlm.nih.gov/pubmed/28734204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2017.07.003
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