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Molecular dynamics of conformation-specific dopamine transporter-inhibitor complexes
The recreational psychostimulant cocaine inhibits dopamine reuptake from the synapse, resulting in excessive stimulation of postsynaptic dopamine receptors in brain areas associated with reward and addiction. Cocaine binds to and stabilizes the outward- (extracellular-) facing conformation of the do...
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| Publicado no: | J Mol Graph Model |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599167/ https://ncbi.nlm.nih.gov/pubmed/28734204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2017.07.003 |
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