DUSP5 and DUSP6, two ERK specific phosphatases, are markers of a higher MAPK signaling activation in BRAF mutated thyroid cancers

BACKGROUND: Molecular alterations of the MAPK pathway are frequently observed in papillary thyroid carcinomas (PTCs). It leads to a constitutive activation of the signalling pathway through an increase in MEK and ERK phosphorylation. ERK is negatively feedback-regulated by Dual Specificity Phosphata...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:PLoS One
Main Authors: Buffet, Camille, Hecale-Perlemoine, Karine, Bricaire, Léopoldine, Dumont, Florent, Baudry, Camille, Tissier, Frédérique, Bertherat, Jérôme, Cochand-Priollet, Beatrix, Raffin-Sanson, Marie-Laure, Cormier, Françoise, Groussin, Lionel
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599027/
https://ncbi.nlm.nih.gov/pubmed/28910386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184861
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla