Effect of iron overload on furin expression in wild-type and β-thalassemic mice

Furin is a proprotein convertase enzyme. In the liver, it cleaves prohepcidin to form active hepcidin-25, which regulates systemic iron homeostasis. Hepcidin deficiency is a component of several iron overload disorders, including β-thalassemia. Several studies have identified factors that repress he...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxicol Rep
Egile Nagusiak: Wichaiyo, Surasak, Yatmark, Paranee, Morales Vargas, Ronald Enrique, Sanvarinda, Pimtip, Svasti, Saovaros, Fucharoen, Suthat, Morales, Noppawan Phumala
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2015
Gaiak:
Short Communication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598392/
https://ncbi.nlm.nih.gov/pubmed/28962376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.01.004
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