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CYP3A4 inhibition by Psoralea corylifolia and its major components in human recombinant enzyme, differentiated human hepatoma HuH-7 and HepaRG cells

Psoralea corylifolia (P. corylifolia) is a medicinal plant used primarily in herbal dietary supplements to treat skin diseases, such as vitiligo and psoriasis. Case reports of liver toxicity have recently emerged from its use, which often includes co-administration with other herbal products. In thi...

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Bibliografiske detaljer
Udgivet i:Toxicol Rep
Main Authors: Liu, Yitong, Flynn, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598390/
https://ncbi.nlm.nih.gov/pubmed/28962388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.03.006
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