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Stereoselective Synthesis of Cyclic Guanidines by Directed Diamination of Unactivated Alkenes

A method for a directed stereoselective guanidinylation of alkenes is described. The guanidine unit can be delivered as an intact fragment by a hydroxy or carboxy group, usually with a high level of stereocontrol. After the guanidine delivery, the directing group can be cleaved under exceptionally m...

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Publicado en:Org Lett
Autores principales: Mailyan, Artur K., Young, Kyle, Chen, Joanna L., Reid, Bradley T., Zakarian, Armen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598158/
https://ncbi.nlm.nih.gov/pubmed/27778502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b02778
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