Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease

Cell type-specific changes in neuronal excitability have been proposed to contribute to the selective degeneration of corticospinal neurons in amyotrophic lateral sclerosis (ALS) and to neocortical hyperexcitability, a prominent feature of both inherited and sporadic variants of the disease, but the...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kim, Juhyun, Hughes, Ethan G., Shetty, Ashwin S., Arlotta, Paola, Goff, Loyal A., Bergles, Dwight E., Brown, Solange P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597984/
https://ncbi.nlm.nih.gov/pubmed/28821643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0811-17.2017
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