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Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
Oligodendrocytes associate with axons to establish myelin and provide metabolic support to neurons. In the spinal cord of ALS mice, oligodendrocytes downregulate transporters that transfer glycolytic substrates to neurons and oligodendrocyte progenitors (NG2(+) cells) exhibit enhanced proliferation...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637847/ https://ncbi.nlm.nih.gov/pubmed/23542689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3357 |
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