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Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
Oligodendrocytes associate with axons to establish myelin and provide metabolic support to neurons. In the spinal cord of ALS mice, oligodendrocytes downregulate transporters that transfer glycolytic substrates to neurons and oligodendrocyte progenitors (NG2(+) cells) exhibit enhanced proliferation...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637847/ https://ncbi.nlm.nih.gov/pubmed/23542689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3357 |
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