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Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis
In the fatal disease—amyotrophic lateral sclerosis (ALS)—upper (corticospinal) motor neurons (MNs) and lower somatic MNs, which innervate voluntary muscles, degenerate. Importantly, certain lower MN subgroups are relatively resistant to degeneration, even though pathogenic proteins are typically ubi...
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| Vydáno v: | Acta Neuropathol |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer Berlin Heidelberg
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427160/ https://ncbi.nlm.nih.gov/pubmed/28409282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1708-8 |
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