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Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis
In the fatal disease—amyotrophic lateral sclerosis (ALS)—upper (corticospinal) motor neurons (MNs) and lower somatic MNs, which innervate voluntary muscles, degenerate. Importantly, certain lower MN subgroups are relatively resistant to degeneration, even though pathogenic proteins are typically ubi...
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| Pubblicato in: | Acta Neuropathol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Berlin Heidelberg
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427160/ https://ncbi.nlm.nih.gov/pubmed/28409282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1708-8 |
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