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Cross‐disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology

Neuromuscular junctions are primary pathological targets in the lethal motor neuron diseases spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). Synaptic pathology and denervation of target muscle fibers has been reported prior to the appearance of clinical symptoms in mouse model...

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Detaylı Bibliyografya
Yayımlandı:J Comp Neurol
Asıl Yazarlar: Comley, Laura H., Nijssen, Jik, Frost‐Nylen, Johanna, Hedlund, Eva
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063101/
https://ncbi.nlm.nih.gov/pubmed/26502195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23917
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