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Cross‐disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology

Neuromuscular junctions are primary pathological targets in the lethal motor neuron diseases spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). Synaptic pathology and denervation of target muscle fibers has been reported prior to the appearance of clinical symptoms in mouse model...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Comp Neurol
Egile Nagusiak: Comley, Laura H., Nijssen, Jik, Frost‐Nylen, Johanna, Hedlund, Eva
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063101/
https://ncbi.nlm.nih.gov/pubmed/26502195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23917
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