A yeast model for the mechanism of the Epstein-Barr virus immune evasion identifies a new therapeutic target to interfere with the virus stealthiness

The oncogenic Epstein-Barr virus (EBV) evades the immune system but has an Achilles heel: its genome maintenance protein EBNA1. Indeed, EBNA1 is essential for viral genome replication and maintenance but also highly antigenic. Hence, EBV evolved a system in which the glycine-alanine repeat (GAr) of...

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Bibliographische Detailangaben
Veröffentlicht in:Microb Cell
Hauptverfasser: Lista, María José, Martins, Rodrigo Prado, Angrand, Gaelle, Quillévéré, Alicia, Daskalogianni, Chrysoula, Voisset, Cécile, Teulade-Fichou, Marie-Paule, Fåhraeus, Robin, Blondel, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shared Science Publishers OG 2017
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597793/
https://ncbi.nlm.nih.gov/pubmed/28913345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2017.09.590
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