A yeast-based assay identifies drugs that interfere with immune evasion of the Epstein-Barr virus

Epstein-Barr virus (EBV) is tightly associated with certain human cancers, but there is as yet no specific treatment against EBV-related diseases. The EBV-encoded EBNA1 protein is essential to maintain viral episomes and for viral persistence. As such, EBNA1 is expressed in all EBV-infected cells, a...

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Detalhes bibliográficos
Main Authors: Voisset, Cécile, Daskalogianni, Chrysoula, Contesse, Marie-Astrid, Mazars, Anne, Arbach, Hratch, Le Cann, Marie, Soubigou, Flavie, Apcher, Sébastien, Fåhraeus, Robin, Blondel, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974454/
https://ncbi.nlm.nih.gov/pubmed/24558096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.014308
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