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The θ-defensin retrocyclin 101 inhibits TLR4- and TLR2-dependent signaling and protects mice against influenza infection

Despite widespread use of annual influenza vaccines, seasonal influenza-associated deaths number in the thousands each year, in part because of exacerbating bacterial superinfections. Therefore, discovering additional therapeutic options would be a valuable aid to public health. Recently, TLR4 inhib...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Prantner, Daniel, Shirey, Kari Ann, Lai, Wendy, Lu, Wuyuan, Cole, Alexander M., Vogel, Stefanie N., Garzino-Demo, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597516/
https://ncbi.nlm.nih.gov/pubmed/28729359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A1215-567RR
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