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Humanized θ-Defensins (Retrocyclins) Enhance Macrophage Performance and Protect Mice from Experimental Anthrax Infections

Retrocyclins are humanized versions of the θ-defensin peptides expressed by the leukocytes of several nonhuman primates. Previous studies, performed in serum-free media, determined that retrocyclins 1 (RC1) and RC2 could prevent successful germination of Bacillus anthracis spores, kill vegetative B....

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Bibliographische Detailangaben
Hauptverfasser: Welkos, S., Cote, C. K., Hahn, U., Shastak, O., Jedermann, J., Bozue, J., Jung, G., Ruchala, P., Pratikhya, P., Tang, T., Lehrer, R. I., Beyer, W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165295/
https://ncbi.nlm.nih.gov/pubmed/21768520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00267-11
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