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Re-engineering the Immune Response to Metastatic Cancer : Antibody-Recruiting Small Molecules Targeting the Urokinase Receptor
Developing selective strategies to treat metastatic cancers remains a significant challenge. Herein, we report the first antibody-recruiting small molecule (ARM) that is capable of recognizing the urokinase-type plasminogen activator receptor (uPAR), a uniquely overexpressed cancer cell-surface mark...
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| Publicado no: | Angew Chem Int Ed Engl |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5597302/ https://ncbi.nlm.nih.gov/pubmed/26879524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201510866 |
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