p53-mediated suppression of BiP triggers BIK-induced apoptosis during prolonged endoplasmic reticulum stress

Physiological and pathological conditions that affect the folding capacity of the endoplasmic reticulum (ER) provoke ER stress and trigger the unfolded protein response (UPR). The UPR aims to either restore the balance between newly synthesized and misfolded proteins or if the damage is severe, to t...

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Bibliografiska uppgifter
I publikationen:Cell Death Differ
Huvudupphovsmän: López, Ignacio, Tournillon, Anne-Sophie, Prado Martins, Rodrigo, Karakostis, Konstantinos, Malbert-Colas, Laurence, Nylander, Karin, Fåhraeus, Robin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596431/
https://ncbi.nlm.nih.gov/pubmed/28622297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.96
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