High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1

Although much is known about transcriptional networks that control embryonic stem cell (ESC) self-renewal and differentiation, the metabolic regulation of ESC is less clear. Autophagy is a catabolic process that is activated under both stress and normal conditions to degrade damaged organelles and a...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Liu, Pinglei, Liu, Kun, Gu, Haifeng, Wang, Weixu, Gong, Jiaqi, Zhu, Yingjie, Zhao, Qian, Cao, Jiani, Han, Chunseng, Gao, Fei, Chen, Quan, Li, Wei, Jiao, Jianwei, Hu, Baoyang, Zhou, Qi, Zhao, Tongbiao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596427/
https://ncbi.nlm.nih.gov/pubmed/28622295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.90
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