Blocking endothelin-1-receptor/β-catenin circuit sensitizes to chemotherapy in colorectal cancer

The limited clinical response to conventional chemotherapeutics observed in colorectal cancer (CRC) may be related to the connections between the hyperactivated β-catenin signaling and other pathways in CRC stem-like cells (CRC-SC). Here, we show the mechanistic link between the endothelin-1 (ET-1)/...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Differ
Main Authors: Cianfrocca, Roberta, Rosanò, Laura, Tocci, Piera, Sestito, Rosanna, Caprara, Valentina, Di Castro, Valeriana, De Maria, Ruggero, Bagnato, Anna
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596423/
https://ncbi.nlm.nih.gov/pubmed/28708138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.121
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