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Blocking endothelin-1-receptor/β-catenin circuit sensitizes to chemotherapy in colorectal cancer
The limited clinical response to conventional chemotherapeutics observed in colorectal cancer (CRC) may be related to the connections between the hyperactivated β-catenin signaling and other pathways in CRC stem-like cells (CRC-SC). Here, we show the mechanistic link between the endothelin-1 (ET-1)/...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5596423/ https://ncbi.nlm.nih.gov/pubmed/28708138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.121 |
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