Common genetic heterogeneity of human interleukin-37 leads to functional variance

Interleukin-37 (IL-37) is an inhibitory member of the IL-1 family of cytokines. We previously found that balanced selection maintains common variations of the human IL37 gene. However, the functional consequences of this selection have yet to be validated. Here, using cells expressing exogenous IL-3...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Yan, Jingjing, Zhang, Yuling, Cheng, Shimeng, Kang, Bin, Peng, Jinbiao, Zhang, Xiaodan, Yuan, Meichun, Chu, Wenqi, Zhang, Wen, Shen, Jiayin, Zhang, Shuye
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596243/
https://ncbi.nlm.nih.gov/pubmed/27665946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.48
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