Common genetic heterogeneity of human interleukin-37 leads to functional variance

Interleukin-37 (IL-37) is an inhibitory member of the IL-1 family of cytokines. We previously found that balanced selection maintains common variations of the human IL37 gene. However, the functional consequences of this selection have yet to be validated. Here, using cells expressing exogenous IL-3...

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Dades bibliogràfiques
Publicat a:Cell Mol Immunol
Autors principals: Yan, Jingjing, Zhang, Yuling, Cheng, Shimeng, Kang, Bin, Peng, Jinbiao, Zhang, Xiaodan, Yuan, Meichun, Chu, Wenqi, Zhang, Wen, Shen, Jiayin, Zhang, Shuye
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596243/
https://ncbi.nlm.nih.gov/pubmed/27665946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.48
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