Enhanced human enterovirus 71 infection by endocytosis inhibitors reveals multiple entry pathways by enterovirus causing hand-foot-and-mouth diseases

BACKGROUND: Human enterovirus 71 (EV71) was previously known to enter cells through clathrin or caveolar mediated endocytic pathways. However, we observed chlorpromazine (CPZ) or dynasore (DNS), which inhibit clathrin and dynamin mediated endocytosis, did not suppress EV71 cell entry in particular c...

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Veröffentlicht in:Virol J
Hauptverfasser: Yuan, Meichun, Yan, Jingjing, Xun, Jingna, Chen, Chong, Zhang, Yuling, Wang, Min, Chu, Wenqi, Song, Zhigang, Hu, Yunwen, Zhang, Shuye, Zhang, Xiaoyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751926/
https://ncbi.nlm.nih.gov/pubmed/29298696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0913-3
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