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Functional dissection of hematopoietic stem cell populations with a stemness-monitoring system based on NS-GFP transgene expression

Hematopoietic stem cells (HSCs) in a steady state can be efficiently purified by selecting for a combination of several cell surface markers; however, such markers do not consistently reflect HSC activity. In this study, we successfully enriched HSCs with a unique stemness-monitoring system using a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ali, Mohamed A. E., Fuse, Kyoko, Tadokoro, Yuko, Hoshii, Takayuki, Ueno, Masaya, Kobayashi, Masahiko, Nomura, Naho, Vu, Ha Thi, Peng, Hui, Hegazy, Ahmed M., Masuko, Masayoshi, Sone, Hirohito, Arai, Fumio, Tajima, Atsushi, Hirao, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596002/
https://ncbi.nlm.nih.gov/pubmed/28900302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11909-3
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