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Sclerostin induced tumor growth, bone metastasis and osteolysis in breast cancer

Breast cancer is the second leading cause of cancer-related deaths among women worldwide. Many patients suffer from bone metastasis. Sclerostin, a key regulator of normal bone remodeling, is critically involved in osteolytic bone diseases. However, its role in breast cancer bone metastasis remains u...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Zhu, Menghai, Liu, Changzhen, Li, Shifei, Zhang, Shudong, Yao, Qi, Song, Qingkun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595999/
https://ncbi.nlm.nih.gov/pubmed/28900298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11913-7
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