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Photobleaching in STED nanoscopy and its dependence on the photon flux applied for reversible silencing of the fluorophore

In STED (stimulated emission depletion) nanoscopy, the resolution and signal are limited by the fluorophore de-excitation efficiency and photobleaching. Here, we investigated their dependence on the pulse duration and power of the applied STED light for the popular 750 nm wavelength. In experiments...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oracz, Joanna, Westphal, Volker, Radzewicz, Czesław, Sahl, Steffen J., Hell, Stefan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595794/
https://ncbi.nlm.nih.gov/pubmed/28900102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09902-x
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