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Montelukast reduces inhaled chlorine triggered airway hyperresponsiveness and airway inflammation in the mouse

BACKGROUND AND PURPOSE: Cysteinyl leukotrienes (CysLTs) are pro‐inflammatory lipid mediators that exacerbate disease state in several asthma phenotypes including asthma induced by allergen, virus and exercise. However, the role of CysLTs in irritant‐induced airway disease is not well characterized....

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Hamamoto, Yoichiro, Ano, Satoshi, Allard, Benoit, O'Sullivan, Michael, McGovern, Toby K, Martin, James G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595758/
https://ncbi.nlm.nih.gov/pubmed/28718891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13953
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