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Montelukast reduces inhaled chlorine triggered airway hyperresponsiveness and airway inflammation in the mouse

BACKGROUND AND PURPOSE: Cysteinyl leukotrienes (CysLTs) are pro‐inflammatory lipid mediators that exacerbate disease state in several asthma phenotypes including asthma induced by allergen, virus and exercise. However, the role of CysLTs in irritant‐induced airway disease is not well characterized....

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Br J Pharmacol
Κύριοι συγγραφείς: Hamamoto, Yoichiro, Ano, Satoshi, Allard, Benoit, O'Sullivan, Michael, McGovern, Toby K, Martin, James G
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595758/
https://ncbi.nlm.nih.gov/pubmed/28718891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13953
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