Methylation of the ribosomal RNA gene promoter is associated with aging and age‐related decline

The transcription of ribosomal RNA genes (rDNA) is subject to epigenetic regulation, as it is abrogated by the methylation of CpG dinucleotides within their promoter region. Here, we investigated, through Sequenom platform, the age‐related methylation status of the CpG island falling into the rDNA p...

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Bibliografske podrobnosti
izdano v:Aging Cell
Main Authors: D'Aquila, Patrizia, Montesanto, Alberto, Mandalà, Maurizio, Garasto, Sabrina, Mari, Vincenzo, Corsonello, Andrea, Bellizzi, Dina, Passarino, Giuseppe
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595699/
https://ncbi.nlm.nih.gov/pubmed/28625020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12603
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