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Global DNA methylation in old subjects is correlated with frailty

Epigenetic variations have been widely described to occur during the aging process. To verify if these modifications are correlated with the inter-individual phenotypic variability of elderly people, we searched for a correlation between global DNA methylation levels and frailty. We found that the g...

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Hlavní autoři: Bellizzi, Dina, D’Aquila, Patrizia, Montesanto, Alberto, Corsonello, Andrea, Mari, Vincenzo, Mazzei, Bruno, Lattanzio, Fabrizia, Passarino, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260357/
https://ncbi.nlm.nih.gov/pubmed/21336567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9216-6
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