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Global DNA methylation in old subjects is correlated with frailty

Epigenetic variations have been widely described to occur during the aging process. To verify if these modifications are correlated with the inter-individual phenotypic variability of elderly people, we searched for a correlation between global DNA methylation levels and frailty. We found that the g...

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Detalhes bibliográficos
Main Authors: Bellizzi, Dina, D’Aquila, Patrizia, Montesanto, Alberto, Corsonello, Andrea, Mari, Vincenzo, Mazzei, Bruno, Lattanzio, Fabrizia, Passarino, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260357/
https://ncbi.nlm.nih.gov/pubmed/21336567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9216-6
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