A cross-section analysis of FT3 age-related changes in a group of old and oldest-old subjects, including centenarians’ relatives, shows that a down-regulated thyroid function has a familial component and is related to longevity

Background: several studies suggest that a decreased thyroid activity might be favourable in oldest-old subjects and that subclinical thyroid hyperfunction may be detrimental. Objectives: to verify whether declining levels of circulating thyroid hormones may contribute to longevity. Design: cross-se...

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Bibliographic Details
Main Authors: Corsonello, Andrea, Montesanto, Alberto, Berardelli, Maurizio, De Rango, Francesco, Dato, Serena, Mari, Vincenzo, Mazzei, Bruno, Lattanzio, Fabrizia, Passarino, Giuseppe
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956534/
https://ncbi.nlm.nih.gov/pubmed/20843963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ageing/afq116
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