Methylation of the ribosomal RNA gene promoter is associated with aging and age‐related decline

The transcription of ribosomal RNA genes (rDNA) is subject to epigenetic regulation, as it is abrogated by the methylation of CpG dinucleotides within their promoter region. Here, we investigated, through Sequenom platform, the age‐related methylation status of the CpG island falling into the rDNA p...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: D'Aquila, Patrizia, Montesanto, Alberto, Mandalà, Maurizio, Garasto, Sabrina, Mari, Vincenzo, Corsonello, Andrea, Bellizzi, Dina, Passarino, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595699/
https://ncbi.nlm.nih.gov/pubmed/28625020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12603
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