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Methylation of the ribosomal RNA gene promoter is associated with aging and age‐related decline
The transcription of ribosomal RNA genes (rDNA) is subject to epigenetic regulation, as it is abrogated by the methylation of CpG dinucleotides within their promoter region. Here, we investigated, through Sequenom platform, the age‐related methylation status of the CpG island falling into the rDNA p...
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Publicado no: | Aging Cell |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5595699/ https://ncbi.nlm.nih.gov/pubmed/28625020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12603 |
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