Beneficial effects of glatiramer acetate in Huntington’s disease mouse models: evidence for BDNF-elevating and immunomodulatory mechanisms

Huntington’s disease (HD) is a fatal, neurodegenerative movement disorder that has no cure and few treatment options. In these preclinical studies, we tested the effects of chronic treatment of glatiramer acetate (GA; Copaxone®), an FDA-approved drug used as first-line therapy for MS, in two differe...

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Bibliographic Details
Published in:Brain Res
Main Authors: Corey-Bloom, Jody, Aikin, Alaina M., Gutierrez, Ashley, Salam, Jwan, Howell, Taylor, Thomas, Elizabeth A.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595665/
https://ncbi.nlm.nih.gov/pubmed/28823953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2017.08.013
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