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Salivary levels of total huntingtin are elevated in Huntington’s disease patients

Patients with Huntington’s disease (HD), an autosomal-dominant neurodegenerative disease, show substantial variability in age-of-onset, symptom severity and course of illness, warranting the need for biomarkers to anticipate and monitor these features. The HD gene encodes the disease protein hunting...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Corey-Bloom, Jody, Haque, Ameera S., Park, Sungmee, Nathan, Ajay S., Baker, Robert W., Thomas, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943337/
https://ncbi.nlm.nih.gov/pubmed/29743609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25095-3
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