Platelet-Targeted Delivery of Peripheral Blood Mononuclear Cells to the Ischemic Heart Restores Cardiac Function after Ischemia-Reperfusion Injury

One of the major hurdles in intravenous regenerative cell therapy is the low homing efficiency to the area where these cells are needed. To increase cell homing toward areas of myocardial damage, we developed a bispecific tandem single-chain antibody (Tand-scFv(Sca-1+GPIIb/IIIa)) that binds with hig...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Ziegler, Melanie, Wang, Xiaowei, Lim, Bock, Leitner, Ephraem, Klingberg, Franco, Ching, Victoria, Yao, Yu, Huang, Dexing, Gao, Xiao-Ming, Kiriazis, Helen, Du, Xiao-Jun, Haigh, Jody J., Bobik, Alex, Hagemeyer, Christoph E., Ahrens, Ingo, Peter, Karlheinz
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595126/
https://ncbi.nlm.nih.gov/pubmed/28900504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.19698
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